I'm not a fan of ballistic reticle scopes, simply because it is near impossible to hope that your gun actually shoots where the marks are on it. At 300 yards a modest velocity difference or even scope mount height can affect the drop enough to cause problems.

IMHO the 250gr is the least attractive of the family...the 200 will shoot flatter and, if I recall the calculations right, actually retain more energy at extended ranges despite its lower weight. The 300 starts slower but shoots about the same trajectory due to its improved BC and hits harder.

But the 250gr load pushed with 150gr is a 300yd load, as long as you know where you're hitting with the scope marks.