Let's really think about this for a minute. If guy's on TV can shoot Pronghorn with a compound bow, we surely can practice are hunting skills enough to get close to shoot a Deer with a pistol bullet from a Muzzleloader. The guy's who say it doesnt matter are the guy's scouting area's to hunt to keep the shot around 50 to 100yds.
Of course the BC matters when you are shooting over two hundred yards for sure. I agree 100%. There are only a select few that hafto or want to shoot there animals over 200yards with a ML. As Spaniel mentioned, you will be really shocked what a 10mph wind will do to a XTP at 225yards.