If Weatherby is what you like then go for it. However it would be near the bottom of the list for me. IMO they are very over priced and do not produce the kind of accuracy I would demand with the price tags they have.
I agree with driftrider and RR. Build a custom rifle. Choose the wood or synthetic stock, the barrel, the chambering, and the action. Build it the way you want it not the way some engineer thinks you want it.