wyheadhunter, I used to use my 22-250 for many years, but I don't plan on using it again any time soon, since I've switched to my AR .204 with berger bullets. Of the nearly 70+ that I've shot in the last two seasons, I lost 3, none last year, and of those 3 none of them were standing shots, all runners, and bullet placement is most likely the blame for the lost coyotes. The bergers simply work! Aim for the shoulder on those broadside shots, and love the frontal chest shot!