Actually they are not the same diameter -- the 250gr is .452 and the 200gr is .40. This means the trajectory and retained energy are event better.

I have taken north of 2 dozen deer with the 200SW at ranges from 20 to 338 yards. Vast majority were pass-thrus and none went any unreasonable distance (haven't made a non-vital hit with the bullet yet). The bullet holds together better than the 250gr variety, probably due to the longer length-for-caliber. I have only had two that obviously separated the core from the jacket, both went through both shoulder blades before doing so and retained the jacket under the far side skin -- and neither deer took a step.

It is an excellent bullet, I would not expect the kind of blood trails you see from .45 caliber hollowpoint projectiles but if you put the bullet in the vitals they work excellent and typically bleed fine. In other words, if you are in the swamp where a 50 yard run is a tragedy I would not recommend it but otherwise go for it.