TNHagies,
That's a very good question. There have been other animals shot with these 250grn bullets out of a Muzzleloader. I would bet they were at a much lower velocity then i was shooting. I will get that information asap.
In my opinion they will perform the same at standard Inline velocities. 1600fps and up i see no problem at all. That's just an opinion and i will find out what loads Dave's (Lehigh)nephew shot his Deer with and the results.