Jaw3
To answer your question accurately we need to know what the load is going to be used for;
for and what caliber you will be shooting.
The two most common situations would be deer and boar if you live where there are some also target shooting a god part of the year. Will assume a 50 cal inline as its the most common.
If you wish to set up for long range some thing like a 200gr SW with 120 gr of Blackhorn this load gives about 2145 average FPSin one of my guns I use the 250 SW in the other with 120 gr Blackhorn fora 2075 average FPS if you like 777-FFF it gives about the same velocity but I find it much harder to get equalaccuracy with that heavy a load and scrubbing out the crud ring every shot wont happen to me any more. Lee