RE: Which Varmint Caliber Should I Buy?
You'd be hard pressed to beat the .22-250. I love that little cartridge. However, the .223 is a great little round too. Unless you shoot a lot past 300 yards, the difference in the two will be minimal. Given that choice, I'd say it really depends on your ammo budget and how much you want to shoot it. If you only plan to shoot only a few rounds at a time, you handload, or you have a larger ammo budget, go with the .22-250 for sure. If you want to shoot a lot and don't handload and have a tight budget, you'll get more bang for your ammo buck with the .223 Rem. You'll give up a small amount of range, but ammo is much cheaper, factory loaded bullet selection is somewhat better.
My preference would be toward the .22-250. It's a great little round that is lightning death to any varmint unfortunate enough to be on the receiving end of the rifle. I've also been able to achieve outstanding accuracy with both factory and hand loads, and the .22-250 isn't too finiky about loads, either.
Mike