Nothing wrong with the Vanguard as it’s made well and they are fairly accurate. They have adjustable triggers to boot. The Sub-MOA models are hand picked from the factory that shoot to that designation. They also have a better stock than the plain injected molded ones.

The Mark V has better quality yet and a shorter bolt throw. My factory Accumark (.300 wby) comes with a heavy contour stainless fluted Krieger barrel, Bell & Carlson hand laminated stock with bedding plate, and Pachmayr Decelerator recoil pad. It too has an adjustable trigger and tight tolerances in the action. My first Mark V was a deluxe model also in .300 wby. Both produce less than 1-inch groups at 100 yards.

The German models tend to bring a little more money on the used market. This is due to that they are no longer made there but, not any better.

For large game, there is no better combination for me than the Mark V in .300 wby mag. Both the Weatherby Mark V and .300 wby cartridge have a track record on game world wide equaled by few others.