I own 2 .17 hmr and 1 .22 mag. They both have there pros and cons. The .17 hmr is so accurate. Its a very flat shooting rifle. I either shoot tnt or v-max in my rifle. The tnt penetrate a little more then the v-max does but the v-max is like what ever you shoot swallowed a grenade. I would feel comfortable taking a coyote at 150 yards with my .17 hmr, because the gun is so accurate. The .22 mag on the other hand is a heavier bullet which flies slower. My .22 mag is very accurate though I have no complaints with it. But you can not beat how flat shooting the .17 hmr is. If I had only one choice 4/5 times id choose the .17 hmr. As the other folks say check out varmintal.com there is a very very good review on there.