All i load and shoot are nosler bt's. I've had excellent luck with them in 223,243,6mm,270,30-06. Havent seen a bullet failure and heavy bone doesnt stop em at all. I watched my father shoot a deer at 10yd with them last yr and they did not explode 150gr outa 30-06. I've personally shot deer with 270 at 30yd and they performed great.