There is one thing that no one can deny; if you can not hit an animal in the right spot you are not doing the job right.
The first requirement is reasonable accuracy, two identical guns may need different bullets to get good consistent accuracy.
I use XTP's in the system One and the Thunderhawk, The Omega shoots Gold Dots and SW's The Triumph shoots Gold Dots and SW's and FTX's the FTX has not been tested on any thing as far as I know except that I am happy with the accuracy the first time out if it continues to be that accurate AND provides penetration and expansion it may well be my go to bullet. Some of my guns do not shoot some of these bullets with good consistent accuracy so I do not use them in that particular gun. The only other point I wish to make is that I use the XTP at 1800 FPS or less; they are not nearly as effective if they are over driven and come apart.