For years i shot 150grn bullets in my 30.06 for deer and had good luck with just about any brand out there. My best performing and accurate bullet in 150grn was the Hornady Spire point. I know alot of people don' t like to go lighter than 150grn for deer with the 06 but about 6 years ago i started loading and using the Hornady 130grn Spire point for deer with excellent results. If i were going on a pay hunt in another state i would load something heavier but an average deer here in my area weighs about 140 and every once in a while you may see one go near 170/190 if you' re lucky. I' ve killed a lot of deer with this bullet and can honestly say i' ve never lost a deer using the 130grn bullet and killed my biggest ever last fall with it that was 180lbs. All but a couple of the deer i' ve shot with the 130grn bullet have fell in their tracks and the couple that did run didn' t go more than 50yds. Every deer i' ve shot with this bullet has been a pass through with the exception of a couple and those were lodged in the skin on the opposite side after going through both shoulders and they were a perfect mushroom. I think as long as you choose your shots wisely and put the bullet in the vitals it' s gonna kill.