RE: .243 Big Game Animals
As far as losing deer to a 243, I have seen just as many lost with a 30-06 as a 243.You put a bullet in a vital area with a decent bullet and you will have a dead deer. the 243 is a great deer gun.
That said, NO, I would never shoot at a moose at any range with a 243 unless he was already wounded. I think the reason people say that moose are not that hard to kill is that they don't run after beingshot like a deer or elk, so you can keep shooting. They are huge animals with thick hide, big bones, and lots of meat.Sure, you can thread a bullet in between a rib into the lungs, and it would be dead quickly, but everything would have to be ideal. Please respect them more than to shoot them with a 243.