If you are just wanting to kill coyotes and don't give a rats batooty about trying to sell the hide, than there are better choices. BUT for every big hole blown out the back side of a coyote, $4. comes off of the lowly $10. price that they are worth.
Of the 64 coyotes that I've shot with my .204, I lost 3. Simply do to bad bullet placement, no blame can go to the caliber or bullet. I do reload and have used the 35 and 40 gr. bergers, and they both seem to work very well.

Some guys seem to think that you gotta use a .25 cal. even. [8D]