I have been able to shoot gophers consistantly with a 22LR well past 100 yards. I have never used a range finder to measure the actual distance of my longest shot, but I am estimating a good 150 yards. It is common to have a 125 yard shot, but you need to have a day with very little to no wind for anything approaching 100 yards. IMO, you should really use a soft leadbullet with a deep, aggressive hollow point for those long shots (Winchester X-Pert Hollow Pointis one) to provide a clean kill. Some of the 22LR bullets that call themselves a hollow point are a jokefor a hollow point bullet. Check to make surewhat type of bullet is legal in your area for hunting and/or possession.