You can shoot any sight out to 50 yards if you have a pin for it. You mention adjustable sights, but I would only caustion you on one thing. A 50 yard shot is not a gimme under any circumstances and misjudge by 3 yards and you have a complete miss. Or the animal takes a step and you end up with a gut shot. For these reason I would recommend that if you don't have time to range the animal and take the 2 seconds to adjust the sight accordingly then that "fast" shot probably shouldn't be taken.