The big factor will be accuracy, recoil, and cost of shooting.
The .270 Winchester is a great deer rifle.....but so are a lot of other less punishing rifles.
At the range from a sand bag or shooting prairie dogs the .270 can be punishing.....it's not a fun gun to shoot....it's a serious hunting rifle much like a .30-06. It will substitute for a varmint rifle but best for infrequent types of varminting like woodchucks and coyotes where one ofter shoots less than five rounds a day.
IMO you would be far better served with something like a .257 Roberts or a .243 Winchester or a .260 Remington or 6.5 X 55 Mauser! or .25-06.....it's up to you