there all good calibers. choose what you think will do the best for what you hunt.

I personally shoot the .300WSM. I use it on whitetails, Mule Deer and Elk and if i ever draw some other tags ill use it on whatever they are. Alot of shot variation, from 180 accubond on elk to 150gr for deer and antelope. its flat and powerful. Short action also makes it smaller and lighter in most cases.