Ahhh the ole' .308, .270, 7mm, 30-06 question. I'll simply quote the great tome Cartridges of the World. "Discussing which of these rounds is superior is akin to the ancient Greek pastime of discussing how many spirits can dance on a pin head." I personally believe the 30-06 is the best overall round. But I do own a .308 and there isn't much a 30-06 can do that a .308 loaded properly wont. However, I feel the .308 would serve you well for varmint shooting. Just lighten the load. As for deer the .308 will put them down with ease. It's a strong choice for all around caliber.