I'd say the .30-06 is the best all around cartridge. Even though I love my Savage .308 and its legendary accuracy, the .30-06 can do more.
You can tone down a .30-06 where it's recoil is lighter than a .308 - heck, almost the recoil of a .30-30!! Or you can load it up heavy, and have the shoulder busting recoil of .338 Winchester Magnum!
But anyway, I chose my .308 because it a NATO cartridge, ammo and brass are everywhere, it can take game up to a moose with proper bullet placement, and well... My Savage .308 just felt right to me and said,
"Buy me and take me home".