It's way to much if you want to keep the furs,if not it will kill them as far as you can hit them.If you are looking to save the hides try a 223,204 or 22-250 or something like that.If this is the only gun you have that is suitable and you dont want to buy a new gun for coyotes then I would shoot everyone I saw with it and not worry about it,just dont expect to sell the furs with a large hole in them,sometimes they can be sewn back and sometimes there is peices missing.Have Fun.