Find the most dominant dog and the runt. Take both out of your selection. Not to say these are bad dogs. I've seen litter runts that end up absolute champions. The dominant dog in the right hands can be a killer team. For the average dog owner, neither would be the best choice.

Take what is left (with your sex preference) and do whatever you want. I really like the idea of letting the wife or kids pick it out.

If you've done your homework and have chosen a breeder that produces the type of dog you like, you will end up with the dog you want.