All the varmint calibers i have are...17 rem, 221 fireball, 218 bee, 223 AI, 204 ruger, 220 swift, 22-250 AI, and 22 hornet. I hunt for fur so thats why i like to use the smaller calibers. The 220 swift and the 22-250 AI are mostly used when im long range smaller varmint hunting like prairie dogs, groundhogs and such...so basically to blow all holy hell outta stuff.