Im fairly tall and while not a big guy, Im not small either. I have a 30/30, 7mm rem mag, and a 300 ultra that I use for hunting. Of those, never scored with the 300 ultra, and have taken a few with the 7mm, and a couple with the 30/30. The little lever doesnt do much for damage, while the 7mm mag does noticeably more. One thing to keep in mind, your choice of bullet design is as much of a factor as caliber. A hard cast lead bullet in a 45/70 probably isnt going to do much damaged compared to a softpoint or hollowpoint, or partition/Aframe versus an accubond etc.
Of the rifles named, the 300 is the most accurate, but I like the 30/30 and 7mm mag the best, and admittedly, the 300 is overkill,lol.