I don' t RECOMMEND a .22 of any kind for game as large as deer. However, as Jack O' Connor' s Indian gude once told him, during a similar debate in a sheep hunting camp in B.C., " Any gun good, shoot ' em good!!"
The Eskimos now use the .222 and .223 almost exclusively, as opposed to their previous selection (the .22 Hornet), and they regularly kill game up to polar bear and walrus with these pipsqueaks!! They are avid reloaders, due to cost of ammo. They don' t lose much game, and they don' t get et up very often, either!!