RE: 270?
When I hunted with my 270, I don' t recall a deer making it out of sight.
I used hot handloads with 130 gr Hornady, worked excellent.
I used 140 gr Ballistic tips, oh my lord like the hammer of Thor!
If you don' t reload, my favorite was the Federal Classic series 130 gr, I think they used Sierra bullets. Excellent results.
I have never had any problems with Corelokts though.
You say bullets in the vitals, but where in the vitals? I believe, (no scientist) that if you hit them high in the chest, it takes them longer to go down. Same with too far back.
I try (stress try) to hit them in the little " pocket" right above the elbow and tight behind the shoulder when I can. This usually wrecks major plumbing as well as lungs and they don' t go far.
Just my $.02
KC