I have killed a couple of deer with my .270, using 130 gr. core lokts. Some were perfect double lung hits, some were a little higher than what I wanted, but they all died quickly. The furthest a deer ran with a " perfect" shot was less than 50 yards. The shots that ended up a little higher than the lungs made the deer drop in their tracks. I think core lokts work great, I also think the .270 works even better. I just think deer react differently to being shot.