According to my records I have the 250g SW with a BC of .184 not .21, if you go with a 150 yard zero you get this:
So your about 3.5" high at 100 yards and your shooting thru a 6" pipe from 0 to 175. Most MLer bullets drop off the wall at 200, you can get a Barnes 300g Spire Point 45/70 to 200 with a 3.5" high zero at 100 yards. Chap