2 Large does this year with a 53# DAS - 420gr arrow with 4 blade Stinger.
1st blew thru ribs/lungs - 40 yd recovery - 135lbs dressed.
2nd thru shoulder paddlebone, lungs and broke offside leg - less then 10 yd recovery - 120lbs dressed.

Shot placement is the key - way more deer lost to bad placement for whatever the reason, then to lack of penetration.

Good luck on the trip.

Steve