If you have an in-line and you suspect that the charge might be foulded. You could probably remove the plug and dump the powder, push the bullet back toward the muzzle slightly, load the powder thought the breech, re-install the plug, then re-seat the bullet. I am just thinking but I guess that would work. You would have to make sure that you don't have tons of breech plug grease on the threads to fould the powder.