I would stick with my current battery:

.41 magnum Taurus Titanium revolver, backpack scouting trail gun.

.223 single shot handi rifle for coyotes, Win 45gr factory loads

.25-06 stainless Ruger Mark II rifle for deer and antelope, 117gr Sierra Gameking handloads.

.300 win mag, stainless H-S Precision rifle for bears and elk, 180gr Nosler Partition handloads.

I have tried a lot of calibers over the years and these are the best suited calibers for me for the game I hunt here in Idaho.