Try 250 SW in a harvestor sabot with 100-110-120gr BH should tell you all you need to know.
Another good load is 250 Gold Dot with a MMP-HPH 24 and 90-100-110 gr BH.
Another is the 200gr SW with the supplied sabot and 90-100-110-120gr BH.
If you are going after elk or bigger use the 300gr SW bonded.
The new PFB also shoots well but its a conical with a more arched trajectory.
Lee