The Omega BDC ballisticsare designed based on using 150 gr load with a 250gr bullet. Most people buy the BDC with the thought that the BDC addresses the hold over required at the extended range. This is very true if you are using the same bullet weight and load that the BDC was designed to. You use a different load and you have created a variable.

Most mzlr sweet spots for accuracyare around 90-120 gr load range. Using 150gr load will get you about 175 -300fps faster than, say a 100gr load. The difference that this FPS makes out at extended ranges will result in hitting lower with the 100 gr load...just not sure how much lower.If you shoot within 100 yards then I would think there would be little to no difference.