Very well put Tom. The only thing I could think of trying to add would be the fact that extra long shots take a great scope, loading your own rounds, and a lot of practice. Most of us average hunters are going to be good out to 300 to 350 yards. If you think your shots are going to be 300 yards are less, you are fine with a .223. That being said, if I had to choose only one, it would be my 22.250.

You should also really think about a heavy barrel, because they are very heavy. They are great for stand hunting, but are a chore to carry around.