The REAL 320 would be my choice, and I would stay away from the shoulder bone. It might splatter that lead bullet. Slip it behind the shoulder into the vitals and you should be fine. I have a friend that shoots black bear (from a tree) with a .50 caliber roundball and claims he has never had a problem harvesting them. They do run off, but normally not far and then they lay down and start their death moan.

I personally hunted them with 380 grain REAL in my .54 and also roundball. I never had a boar come in and refused to harvest a small one that was a real clown, but I did not feel under gunned. I hunted from both a tree and a ground blind, but when you have a sow and cub 20 feet from the blind, it does get one worried. I also carried a .44 magnum with me just in case.