I don't recall taking ANY days off, last year....and I hunted 48 times. If I average 4 hour sits (likely)....that's almost 200 hours on stand.
I'm fortunate in that I can come in late on some days.....and take off early on others. I can also hunt every day in the early season, in the evenings.
I plan on 1 or two days vacation to hunt.....but I'll pick them strategically.....and they'll be dependent on what's already been taken. I hope to take ZERO days vacation to hunt.