RE: Your favorite .243 for deer
I've used the CoreLokts, PowerPoints, and Hi-Shoks to about equal effect for years on whitetails, muleys, and pronghorns. My rifle doesn't seem to prefer any one of them over the other in terms of accuracy, though you may not find that the case with your particular rifle.
I've also used handloads and "premiums", and can't say that the extra time or money spent was evident downrange in accuracy or effects on target.
My recommendation: Find one your rifle "likes", if you do your part getting the bullet where it needs to go, the standard factory loads won't fail you.