Why not? I'm planning on using it in my 7mm Rem Mag this fall. The Remmy Managed Recoil ammo has a power level about equal to the 7mm-08, and is reasonably accurate. That said, the recoil of the 7mm 140 gr MR rounds was pretty stout compared to my .243.

According to the Chuck Hawks site, recoil energy for the 100 gr. .243 is 8.8. Recoil energy for the 140 gr. 7-08 is 12.6.