"....I'm gonna pick up a ruger chambered in 270 win to use for kentucky deer and coyotes for now but eventually i'm going to go after mulies, elk, boar, bear (black or griz), antelope, or even caribu. My question is will this be big enough?"
Good luck with your hoped for new acquisition.
Good luck with your hoped for dream hunts.
IMHO, the 30-06 is a better "jack of all trades" rifle since it appears that is what you are looking for; however, decades may pass before you take on all those hunts and in the mean time your choices may change, so....probably no harm done.
The 270 Win was my first centerfire, okay on deer,not all that impressed above that.