I agree with Salukipv!

My son has a New England Firearms .243 single action he uses for deer. This little number is very accurate and occasionally I'll take use it for yotes / deer.

For antelopes I would highly recommend the Federals 80 grain Seirra Game Kings. Shoots flatter then the 100 grain, yet will do a number on lopes / deer. 55 - 75gr are really intended for varmites / predators