I shoot 180 gr ballistic silvertips in my 30-06 and have not had a deer travel more than 30 yds after being hit, in fact that majority drop on the spot. I also shoot 140 gr accubonds and sst's from my 270 WSM with the same result. Location of the shot I feel is the determining factor. If your concerned about it go with a heavy for caliber bullet and it will provide what your looking for.