Over the years i' ve used a 308,7mm-08 & 6.5x55(simular performance to a 260) on medium game(up to about 300 pounds) & all of them are deadly out to about 300 yards.

I' ve fired more rounds through a 308 than any other by A large margin but I do think the 7mm bullets perform better on game of thise size than any other.

I' v owned 3 7mm-08' s 0ver the years,they have all been accurate,pleasant to shoot & deadly on game.

I have found the 130 to 150 grain bullets in my 7mm-08 to be most effective on game.

My vote is definately for the 7mm-08.