ORIGINAL: bigcountry
RL22 wants to run hottttt. Use a magnum primer like the 215 or WLRM. 210 might do ok, as I have had luck with it in a 300RUM. All you can do is try.
I have found that the Federal 210 primers are OK in the .30/'06 lenth belted magnums. It is all I use in the 7mm Rem. Mag. and .308 Norma with extruded powders like H4831, RE 22, and IMR 7828. I do use Federal 215's in the .416 Rigby, but not in the .375 H&H with IMR 4350.....