Buying new? Get a Dan Wesson .445 SuperMag. Considering used? Get a Dan Wesson .44 Magnum. Dan Wessons are arguably the most accurate and durable production double-action revolvers made. (Check their track record in silhouette shooting vs. Ruger or Smith.) You want/need a scoped 10" barrel? It's available. You also want a 4" barrel for a pack-around gun? It's available too and can be used on the same frame so you don't have to buy two weapons. Barrels swap in minutes using a simple wrench and feeler guage; no gunsmithing. If available grips/stocks don't suit you, you can get a blank and carve your own since the grip attaches with a studthat allows nearly any style or size.
Check your game laws carefully. Some states, such as Indiana, determine that a cartridge having a case length longer than a prescribedmaximum is considered a rifle cartridge no matter what it's used in. The .460 S&W Magnum, for example, is illegal in Indiana for deer hunting because it is .175" over maximum length.