I saw a guy drop a buffalon on tv with a neck shot from a .30-30, then from one outfitters website I've seen about how much lead some of these guys can soak up, paraphasing him, he personally had seen a buff take 5 shots from a .300 win mag, all within the size of a small plate, then to hand the client his .375 where he put 3 more in him....

My cousin I know put 3 in his buff with a .338 win mag before having him drop.

To me big and slow sounds better, the .458lott while faster than the .45-70 is much bigger and slower than the other 2. I suppose by the time the hunt, if it happens, rolls around I'll have a much better idea of how the hunt should go.