Getting close and using good shot placement. Most of todays modern youth bows will get numbers close to an average traditional set up which has killed big game for centuries. A pass through is nice, but you can kill an animal without it. You get that arrow in the lungs and the animal will die. Tracking skills don't hurt any either

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I agree with the others, light arrows are ok of you are shooting a really efficient set up, but once you start getting down in draw weight and draw length or us an inefficient bow you should be looking at arrow of at LEAST 400 grns.
Paul