I like to pick stand sites that block deer from coming from a certain direction. The wind does switch a lot (ever sit by a camp fire?). Wind will often blow then back up. I still always play the predominant wind direction! The predominant wind will carry away scent from the minor switches that occur. some of my stands will always have a different wind then when I checked b4 entering the woods. changes in terrain will tend to bend the wind or make it swirl. Just like water in a stream.
Play the predominant wind. use the terrain to block deer. Learn how wind works at your stand sites. Hunt only when the wind is prefect for your site. and do as much as you can to control your scent.