Did this with a pair of Remington slugs from about 20 yards, the one on the left is a regular remington slug, the one of the right is a Buckhammer, both from a 20 ga. The buckhammer was the first time I've had the impact from a 20ga slug knock over a deer. I've made 'em fall, but never straight knocked 'em over.
Here's a hanging pic for size reference I'm 5'11:
That said, I took this guy with regular Remington 20 ga slugs at 30 yards:
I agree with Paul, the most important thing is matching the ammo to your gun and knowing your gun as well as being accurate with it. It's not the Indian, it's the arrow.