First of all you need a fletching jig. There are many brands out there to choose from. I use a Bohning, its great, but im not trying to push it on you. Theres tons of options.

Once you get it, you'll have to play with it some to get the fletchings to sit on the shaft properly. You want to base of the fletching to be completely touching the shaft.

You can offset, left or right. I dont have a helical clamp, but I put my blazers on with a moderate right offset.

It will take a while to get the hang of it, but once you get it set the way you want it, it will be a breeze to fletch arrows

I use a simple razor blade to strip my fletchings and a Scotch Brite pad to smooth the shaft before putting on new fletchings

I also use Bohning glue, but just about any fletching glue will work (assuming you're using carbon arrows).

EDIT: They both beat me to it!